Pregnancy

Pregnancy

Increased Peripheral vasodilators –> NO, Prostacycline –> Reduced SVR –> Mild hypotension –> Activation of RAAS –> Incraeased Water and Na reabsorption –> Fluid retension –> Increased VENOUS RETURN –> INCREASED CARDIAC PRELOAD –> INCREASED CARDIAC OUTPUT!

• INC CO, VR, CARDIAC PRELOAD, stroke volume
• DEC SVR
• NORMAL: Central Venous Pressure

mild hypoproteinemia (because of increased water/na) –> edema fluid retension