Oneliner_763

OneLiner

Lithium is a first-line drug used in the treatment of bipolar disorder: S/S of toxicity: polyuria (nephrogenic diabetes insipidus), weight gain (hypothyroidism/goiter), tremor, polydipsia, gastric distress, and ataxia. Low therapeutic index – needs regular monitoring. Risk of Ebstein anomaly, a congenital cardiac malformation in which the tricuspid valve is displaced inferiorly into the right ventricle -> atrialization of the right ventricle