Oneliner_647

OneLiner

Cytomegalovirus (CMV) retinitis. CMV retinitis is effectively treated with ganciclovir, which is activated by phosphorylation by viral protein kinases and acts as an analog to dGTP, competitively inhibiting the incorporation of dGTP into replicating viral DNA. Ganciclovir’s two significant adverse effects are myelosuppression and nephrotoxicity