Oneliner_368

OneLiner

Parvovirus B19 infection can. Cause transient aplastic crisis, particularly in those with underlying Hb disorders such as sickle cell anemia -> symptomatic anemia (exertional dyspnea, fatigue, low hematocrit, ejection murmur) due to inhibition of erythropoiesis and RBC maturation -> giant pronormoblasts with glassy, intranuclear viral inclusions