Oneliner_325

OneLiner

AIN – causes: Antibiotics (eg, beta-lactam, sulfonamide, rifampin), PPI, NSAID’s, Diuretics, Autoimmune diseases. Clinical features: Rash, fever. Lab Findings: Acute kidney injury, pyuria, hematuria, WBC casts, Eosinophilia, urinary eosinophils, Renal biopsy findings: Inflammatory interstitial infiltrate & edema. AIN is thought to be due to IgE-mediated (type 1) or cell-mediated (Type IV) hypersensitivity.