Oneliner_279

OneLiner

Heparin-induced thrombocytopenia – most common cause of thrombocytopenia in hospitalized pts. Unfractioned heparin > LMWH. Caused by antibodies to heparin & Platelet favor IV. Paradoxical thrombosis. Rx: stop heparin and use of direct thrombin inhibitors (hirudin, lepirudin, argatroban) that do not require antithrombin-III