Oneliner_1922

OneLiner

Ethylene glycol intoxication.» central nervous system sedation, high anion gap metabolic acidosis, flank pain, hematuria, & formation of oxalate crystals. Ethylene glycol is present in antifreeze and is converted to glycolic and oxalic acid by alcohol dehydrogenase. Oxalate anions combine with calcium to produce calcium oxalate crystals that obstruct the renal tubules, causing ATN to nephrotoxic injury. TX: sodium bicarbonate