Oneliner_1875

OneLiner

Muscarinic antagonists, like atropine, act at muscarinic receptors, which block M1(Gq) M2 (Gi) and M3 (Gq). Gq proteins increase phospholipase C, which increases diacylglycerol (DAG) to increase protein kinase C and IP3, which increases Ca2+ causing smooth muscle contraction.