Oneliner_1571

OneLiner

Polycythemia vera is a myeloproliferative disorder that results from a JAK2 mutation, a non-receptor tyrosine kinase. This mutation leads to constitutive activation of the JAK2, signal transducer of activation (STAT) pathway and uncontrolled hematopoietic proliferation. This results in excessive RBCs, WBCs, and platelets