vimatics

vi medicine informatics

Oneliner_1350

by

OneLiner

6-mercaptopurine (6-MP) & Methotrexate disrupt the S phase of the cell cycle. 6-MP is a purine analog that is taken up into DNA during the S phase, halting DNA synthesis and leading to cell death. Its adverse effects include bone marrow, GI, and liver toxicities.

tags: oneliner