vi medicine informatics
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Insulin binds to the insulin receptor that has tyrosine kinase activity. The most important adverse effects of insulin are hypoglycemia and injection site reactions. Sodium-dependent glucose transporter 2 (SGLT-2) inhibitors such as canagliflozin are not safe to prescribe for patients with renal disease. SGLT-2 inhibitors block the reabsorption of glucose in the kidney. Major adverse effects include urinary tract infections, kidney injury, and hypotension.
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