Alcoholism_drug_choices

First Line:

• Mu Opioid Antagonist –> Naltrexone –> Inhibit Reward/Reinforce
  • Can be initiated while patient is drinking
  • decrease alcohol cravings
  • Cannot give in Liver disease (metabolized)
• Acamprosate
  • glutamate modulator
  • Can be used in Liver disease (kidney secrets)

Second Line:

• Aldehyde dehydrogenase inhibitors –> Unable to metabolise ethanol, exaggerates discomfort
• Disulphram: considered second line –> need to be highly motivated –>