Oneliner_513

OneLiner

Consumption of Botulism Toxin has manifestations of both nicotinic blockade (dysphagia & ptosis) & muscarinic blockage (e.g. Dry mouth). It’s a preformed neurotoxin. Inhibits cholinergic nerves, including nicotinic & muscarinic motor neurons. It prevents binding & fusion of Ach containing synaptic vesicles with the plasma membrane through the destruction